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US 5,968,542 AGranted
High viscosity liquid controlled delivery system as a device
AssigneeSouthern BioSystems, Inc.
InventorArthur J. Tipton
Life of this patent
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Abstract
A composition as a medical or surgical device is provided that includes: (i) a non-polymeric, non-water soluble liquid carrier material (HVLCM) of viscosity of at least 5,000 cP at 37.degree. C. that does not crystallize neat under ambient or physiological conditions; and, optionally, (ii) a substance to be delivered.
Claims27
A medical or surgical implant, film, or graft composition comprising:
- a non-polymeric, non-water soluble, high viscosity liquid carrier material having a viscosity of at least 5000 cP at 37.degree. C. that does not crystallize neat under ambient or physiological conditions.
A medical or surgical implantable or sprayable composition comprising a mixture of:
- (a) a non-polymeric, non-water soluble, high viscosity liquid carrier material having a viscosity of at least 5000 cP at 37.degree. C. that does not crystallize neat under ambient or physiological conditions;
- and
- (b) a solvent in which the non-polymeric, non-water soluble liquid carrier material is soluble;
- wherein the mixture has a viscosity of less than approximately 1000 cP at 37.degree. C.
1 more element
A method for the in vivo formation an implant, film, or graft in a patient in need thereof, comprising:
- (1) contacting a mixture comprising:
- (a) a non-polymeric, non-water soluble, high viscosity liquid carrier material having a viscosity of at least 5000 cP at 37.degree. C. that does not crystallize neat under ambient or physiological conditions;
- and
- (b) a solvent in which the non-polymeric, non-water soluble liquid carrier material is soluble;
- wherein the mixture has a viscosity of less than approximately 1000 cP at 37.degree. C.
- with the tissue of the patient;
- and
- (2) allowing the solvent to dissipate or diffuse into the tissue of the patient, thereby forming an implant, film, or graft of the non-polymeric, non-water soluble, high viscosity liquid carrier material.
5 more elements
Dependencies are inferred from the claim text.