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US 5,968,525 AGranted
Inactivated Mycolplasma hyopneumoniae and uses therefor
AssigneeAmbico Inc.
InventorsGerald R. Fitzgerald, C. Joseph Welter
Life of this patent
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Abstract
The invention relates to a method for making an inactivated vaccine of Mycoplasma hyopneumoniae by inactivating the bacteria with Thimerosal. The resulting bacterin is mixed with an adjuvant of aluminum hydroxide and DEAE dextran and injected into pigs. The resulting bacterin and adjuvant mixture can also be mixed with other bacteria such as Bordetella and Pasteurella, for further adjuvant effect. Protective immunity against mycoplasmal pneumonia is elicited in swine using these vaccines.
Claims4
A combination vaccine comprising
- a) an immunogenically effective amount of attenuated or killed Mycoplasma hyopneumoniae bacteria, and
- b) an immunogenically effective amount of at least one other vaccine against a disease of swine.
Dependencies are inferred from the claim text.