Nonaqueous compositions for parenteral administration
AssigneeAmerican Cyanamid Company
InventorsDavid Farley Johnson, James M. Quinlan
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Abstract
The present invention provides nonaqueous compositions comprising a saccharide fatty acid ester and an active compound. The nonaqueous compositions of this invention may be parenterally administered to animals and humans. In particular, the nonaqueous compositions of the present invention are useful for preventing, controlling or treating helminth, acarid or arthropod endo- or ectoparasitic infection or infestation in warm-blooded animals.
Claims22
A nonaqueous composition for parenteral administration which comprises about 0.001 to 25% w/v of a substantially water-insoluble active compound, about 0.1 to 70% w/v of a saccharide fatty acid ester, and about 20 to 99% w/v of a pharmaceutically acceptable water-miscible solvent.
A method for preventing, or treating helminth, acarid or arthropod endo- or ectoparasitic infection or infestation in a warm-blooded animal which comprises parenterally administering to the animal an anthelmintically, acaricidally or arthropod endo- or ectoparasiticidally effective amount of a nonaqueous composition comprising about 0.001 to 25% w/v of a substantially water-insoluble macrolide compound, about 0.1% to 70% w/v of a saccharide fatty acid ester, and about 20 to 99% w/v of a pharmaceutically acceptable water-miscible solvent.
Dependencies are inferred from the claim text.