Androstane steroids as neurochemical initators of change in human hypothalamic compositions and methods
AssigneePherin Pharmaceuticals, Inc.
InventorsDavid L. Berliner, Nathan William Adams, Clive L. Jennings-White
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Abstract
The invention relates to a method of altering hypothalamic function in an individual. The method comprises nasally administering a human semiochemical, e.g. an Androstane steroid, or a pharmaceutical composition containing a semiochemical, such that the ligand semiochemical binds to a specific neuroepithelial receptor. The steroid or steroids is/are preferably administered in the form of a pharmaceutical composition containing one or more pharmaceutically acceptable carriers. Other embodiments of the invention include pharmaceutical compositions containing the steroids.
Claims12
A method of reducing anxiety in an individual comprising the step of administering androsta-4,16-dien-3.beta.-ol.
A method of reducing anxiety in an individual comprising the step of administering to the vomeronasal organ of said individual a unit dosage of up to about 100 micrograms of androsta-4,16-dien-3.beta.-ol.
Dependencies are inferred from the claim text.