US 5,965,458 AGranted

Test strip, its production and use

AssigneeOy Medix Biochemica AB

InventorsIlkka Sakari Kouvonen, Eivor Helena Svens, Sari Hannele Tikanoja, Pekka Antero Turunen, Lauri Markus Sivonen

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Abstract

A test strip for a rapid immunoassay containing specific immunochemical reagent zones (7, 8, 9) is described. The test strip (10) has a backing sheet (1) and attached thereto a receiving end pad (3) and at a distance therefrom a finishing end pad (5). A test membrane (2) is provided between said pads (3, 5). Said membrane (2) is positioned in parallel relationship to said backing (1) at a distance therefrom so that said backing (1) and said membrane (2) limit between themselves an air gap (4) which is open at its edges. Said gap (4) functions as a sheltered reaction chamber for the immunolgical reaction taking place as a liquid is made to flow through said membrane (2). The test strip is simple to manufacture by lamination and easy to use and it is suitable for both diagnostic and environmental immunoassays.

Claims9

Dependent claims

A test strip for a rapid immunoassay which comprises:

a backing member;
a test membrane positioned on said backing member and comprising a first sample absorbing end, at least one label zone downstream of said sample absorbing end, and at least one immunochemical reagent zone located downstream of said label zone;
a first supporting pad positioned on said test membrane upstream of said at least one immunochemical reagent zone;
a second supporting pad positioned on said test membrane downstream of said at least one immunochemical reagent zone;
a cover positioned over said supporting pads in a spaced apart relationship from said test membrane to define top and bottom boundaries of an air gap therebetween, whereby said first and second supporting pads define an upstream and downstream boundary of said air gap and said air gap is open at its edges in a direction perpendicular to said downstream direction, said cover being transparent in a portion thereof which is positioned over said reagent zones.

2 more elements

Dependencies are inferred from the claim text.