Human RAD50 gene and methods of use thereof
AssigneeGenelabs Technologies, Inc.
InventorsGregory Dolganov, Alexander Novikov
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Abstract
Substantially-isolated polynucleotides encoding human RAD50 polypeptides, human RAD50 genomic sequences, and methods of use thereof.
Claims12
A recombinant vector effective to transform human bone marrow cells, comprising
- an expression cassette containing a polynucleotide sequence that encodes (i) an hRAD50 protein encoded by nucleotides 389 to 4324 in SEQ ID NO:44 or (ii) an hRAD50 protein having the sequence identified by SEQ ID NO:47 under control of suitable control elements.
A protein expression vector containing, as a heterologous gene under the control of suitable control elements, a polynucleotide sequence that encodes (i) an hRAD50 protein encoded by nucleotides 389 to 4324 in SEQ ID NO:44 or (ii) an hRAD50 protein having the sequence identified by SEQ ID NO:47.
An isolated polynucleotide fragment containing an open reading frame that encodes (i) an hRAD50 protein encoded by SEQ ID NO:44 or (ii) an hRAD50 protein having the sequence identified by SEQ ID NO:47.
Dependencies are inferred from the claim text.