Promoter
AssigneeZeneca Limited
InventorsIan Jepson, Andrew James Greenland, Michael Bevan, Hilary Sheppard
Life of this patent
Estimating the term…
Abstract
A chemically inducible gene promoter sequence, and particularly, but not exclusively, a chemically inducible gene promoter sequence based on cis regulatory elements from the maize glutathione S-transferase 27 (GST-27) gene. In a preferred embodiment, the promoter sequence is operatively linked or fused to a gene or series of genes whereby expression of the gene or series of genes may be controlled by application of an effective exogenous inducer.
Claims25
An isolated chemically inducible gene promoter sequence having a sequence of the region 1 to 897 base pairs immediately upstream of the transcription start point of the gene promoter sequence of the 27kD subunit of glutathione S-transferase.
An isolated chemically inducible gene promoter sequence having the sequence of the region 1 to 760 base pairs immediately upstream of the transcription start point of the gene promoter sequence of the 27kD subunit of glutathione S-transferase.
An isolated chemically inducible gene promoter sequence having the sequence of the region 1 to 570 base pairs immediately upstream of the transcription start point of the gene promoter sequence of the 27kD subunit of glutathione S-transferase.
An isolated chemically inducible gene promoter sequence having the sequence of the on 1 to 378 base pairs immediately upstream of the transcription start point of the gene promoter sequence of the 27kD subunit of glutathione S-transferase.
An isolated chemically inducible gene promoter sequence having the sequence of the region 267 to 332 base pairs immediately upstream of the transcription start point of the gene promoter sequence of the 27kD subunit of glutathione S-transferase.
An isolated chemically inducible gene promoter sequence having the sequence of the region 275 to 290 base pairs immediately upstream of the transcription start point of the gene promoter sequence of the 27kD subunit of glutathione S-transferase.
An isolated chemically inducible gene promoter element having the sequence of the region 267 to 279 base pairs immediately upstream of the transcription start point of the gene promoter sequence of the 27kD subunit of glutathione S-transferase.
An isolated chemically inducible gene promoter element having the sequence of the region 278 to 288 base pairs immediately upstream of the transcription start point of the gene promoter sequence of the 27kD subunit of glutathione S-transferase.
An isolated chemically inducible gene promoter element having the sequence of the region 286 to 296 base pairs immediately upstream of the transcription start point of the gene promoter sequence of the 27kD subunit of glutathione S-transferase.
An isolated chemically inducible gene promoter element having the sequence of the region 320 to 332 base pairs immediately upstream of the transcription start point of the gene promoter sequence of the 27kD subunit of glutathione S-transferase.
Dependencies are inferred from the claim text.