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US 5,965,358 AGranted
Method for assessing the relative purity of viral gene transfer vector stocks
AssigneeGenVec, Inc.
InventorsMiguel Carrion, Imre Kovesdi
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Abstract
The present method involves evaluating the purity of a viral gene transfer vector stock by providing an aliquot of the viral gene transfer vector stock and producing charged fragments from the aliquot. The fragments are detected by a detector that produces a sample signal corresponding to the mass-to-charge ratio of the detected fragments. This signal then is compared to a standard signal, whereby the purity of the viral gene transfer vector stock is evaluated.
Claims20
A method of evaluating the purity of a viral gene transfer vector stock, the method comprising:
- (a) providing an aliquot of a viral gene transfer vector stock;
- (b) producing charged fragments from the aliquot;
- (c) detecting the fragments by a detector which produces a sample signal corresponding to the mass-to-charge ratio of the detected fragments;
- (d) providing a standard signal;
- and
- (e) evaluating the purity of the viral gene transfer vector stock by comparing the sample signal to the standard signal.
3 more elements
Dependencies are inferred from the claim text.