Process for the production of granules, and granules thus obtained
AssigneeBionatec
InventorsGaetano Zannini, Domenico Boraschi, Dominique Juge, Laurence Matza
Life of this patent
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Abstract
A method for making solid granules containing aromatic, nutritional, dietary or cosmetic substances, wherein a core consisting of excipients optionally combined with active substances is formed for use as a carrier, and the core is coated in three steps with at least one layer, with one layer being formed in each step, by (a) coating the core with active substances optionally combined with excipients, (b) drying the layer and (c) screening the coated core. The method is preferably used to make granules that contain plant extracts and essential oils and may be chewed, sucked, swallowed or dissolved.
Claims10
Process for the production of solid granules, containing substances selected from the group consisting of nutritional, pharmaceutical, and cosmetic substances, which comprises:
- providing a solid core consisting of at least one excipient optionally associated with active substances for use as a support, the excipient or active principle being in solution,
- covering the core, in three steps, with at least one layer, the three steps being carried out for each successive layer, by:
- a) coating the core with active substances optionally associated with excipients, said coating being carried out under vacuum in at least one turbine rotating about an axis,
- b) drying the layer, and
- c) screening the core covered by the dried layer to obtain the solid granules;
- said process being carried out at a humidity of less than 70%, and at a temperature comprised between 18 and 25.degree. C., except for the drying step which is carried out at a maximum temperature of 45.degree. C. in an oven.
Dependencies are inferred from the claim text.