Adhesive matrix type transdermal patch and method of manufacturing same
AssigneeK.K. Holding AG
InventorConstantine Haralambopoulos
Life of this patent
Estimating the term…
Abstract
The invention provides adhesive matrix type transdermal patches and methods for manufacturing the patches. More specifically, the invention utilizes ordinary, prefabricated, commercially available, pressure-sensitive adhesive tapes with skin compatible adhesives, as the structural part of the patch. The adhesive matrix layer of the tape is loaded with the desirable active substances either by embedding, in the case of powders, the active substances in an adhesive matrix layer by the application of heat or pressure, or by a diffusion process for active substances comprising liquids/semi-liquids are carried in located in an embossed release liner or backing layer, which are contact laminated to the adhesive matrix by pressure.
Claims16
A transdermal patch made by the process of:
- depositing an active layer of at least one active substance on an adhesive matrix located on a backing layer of a pressure sensitive adhesive tape, wherein said at least one active substance comprises at least one of a powder, a liquid and a gel;
- bringing a release liner into contact with the adhesive matrix;
- and
- applying pressure to the adhesive matrix to drive the active substance into the adhesive matrix.
A process for manufacturing a transdermal patch comprising the steps of:
- depositing an active layer of at least one active substance on an adhesive matrix located on a backing layer of a pressure sensitive adhesive tape, wherein said at least one active substance comprises at least one of a powder, a liquid and a gel;
- bringing a release liner into contact with the adhesive matrix;
- and
- applying pressure to the adhesive matrix to drive the active substance into the adhesive matrix.
A transdermal patch made by the process of:
- depositing at least one active substance on an adhesive layer of an adhesive transfer in at least one of a random discontinuous pattern and an ordered discontinuous pattern, wherein said at least one active substance comprises at least one of a powder, a liquid and a gel;
- bringing a backing layer into contact with the adhesive matrix;
- and
- laminating the backing layer to the transfer adhesive tape by the application of pressure.
A method of manufacturing a transdermal patch comprising the steps of:
- depositing at least one active substance on an adhesive layer of an adhesive transfer tape in at least one of a random discontinuous pattern and an ordered discontinuous pattern, wherein said at least one active substance comprises at least one of a powder, a liquid and a gel;
- bringing a backing layer into contact with the adhesive matrix;
- and
- laminating the backing layer to the transfer adhesive tape by the application of pressure.
A transdermal patch made by the process of:
- depositing an active substance comprising at least one of a liquid and a semi-liquid into depressions of an embossed liner;
- locating an adhesive tape including an adhesive matrix and a backing layer over the embossed layer, wherein the adhesive matrix is in contact with the embossed liner;
- and
- laminating the embossed liner to the pressure sensitive adhesive tape using heat and pressure.
A method of manufacturing a transdermal patch comprising:
- depositing an active substance comprising at least one of a liquid and a semi-liquid into depressions of an embossed liner;
- locating an adhesive tape including an adhesive matrix and a backing layer over the embossed layer, wherein the adhesive matrix is in contact with the embossed liner;
- and
- laminating the embossed liner to the pressure sensitive adhesive tape heat and pressure.
A transdermal patch made by the process of:
- depositing an active substance comprising at least one of a liquid and a semi-liquid into depressions of an embossed backing;
- locating an adhesive transfer tape including an adhesive matrix and a release liner over the embossed backing, wherein the adhesive matrix is in contact with the embossed backing;
- and
- laminating the embossed backing to the pressure sensitive adhesive transfer tape using heat and pressure.
A method of manufacturing a transdermal patch comprising:
- depositing an active substance comprising at least one of a liquid and a semi-liquid into depressions of an embossed backing;
- locating an adhesive transfer tape including an adhesive matrix and a release liner over the embossed backing, wherein the adhesive matrix is in contact with the embossed backing;
- and
- laminating the embossed backing to the pressure sensitive adhesive transfer tape using heat and pressure.
Dependencies are inferred from the claim text.