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US 5,965,144 AGranted
Chitosan induced immunopotentiation
AssigneeZonagen, Inc.
InventorsJoseph S. Podolski, Mitzi L. Martinez
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Abstract
Methods and compositions for potentiating an immune response are disclosed which incorporate chitosan as an immunopotentiating adjuvant. Administration of the compositions of the invention is effected by various routes.
Claims7
A composition prepared by the process of:
- a) preparing a chitosan solution;
- b) incorporating an antigen into a phosphate buffer to form an antigen/phosphate buffer solution;
- c) lyophilizing the antigen/phosphate buffer solution to a lyophilized mixture;
- and
- d) reconstituting the lyophilized mixture in said chitosan solution to form an antigen/chitosan mixture.
2 more elements
An immunogen prepared by the process of:
- a) preparing a chitosan solution;
- b) incorporating an antigen into a phosphate buffer to form an antigen/phosphate buffer solution;
- c) lyophilizing the antigen/phosphate buffer solution to a lyophilized mixture;
- and
- d) reconstituting the lyophilized mixture in said chitosan solution to form an antigen/chitosan mixture.
2 more elements
A method for producing an immunogen comprising the steps:
- a) preparing a chitosan solution;
- b) incorporating an antigen into a phosphate buffer;
- c) lyophilizing the antigen/phosphate buffer solution to a lyophilized mixture;
- and
- d) reconstituting the lyophilized mixture in said chitosan solution.
2 more elements
Dependencies are inferred from the claim text.