Lymphocyte chemoattractant factor and uses thereof
AssigneeResearch Corporation Technologies, Inc.
InventorsDavid M. Center, William W. Cruikshank, Hardy Kornfeld
Life of this patent
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Abstract
Disclosed is a substantially pure antibody which specifically binds a LCF polypeptide and methods of using such antibodies.
Claims5
A composition for stimulating proliferation of CD4+ T cells in a mammal, said composition comprising lymphocyte chemoattractant factor (LCF) of SEQ ID NO:1 and interleukin-2 (IL-2), wherein said LCF and IL-2 are present in a ratio whereby CD4+ T cell proliferation is synergistically increased relative to LCF or IL-2 alone.
A method for stimulating proliferation of CD4+ T cells in a human infected with human immunodeficiency virus (HIV), said method comprising administering a therapeutically effective amount of a composition comprising lymphocyte chemoattractant factor (LCF) of SEQ ID NO:1 and interleukin-2 (IL-2).
Dependencies are inferred from the claim text.