Glucose sensor
AssigneeImplanted Biosystems Inc.
InventorsElmo A. Blubaugh, Jr., Alan R. Brunsman
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Abstract
A sensor that is capable of accurately measuring glucose and other analytes in low oxygen environments is provided. The sensor employs an enzyme-containing membrane comprising a semi-interpenetrating polymer network which is infiltrated by an enzyme. The enzyme-containing membrane increases oxygen transport to the enzyme such that oxygen is not a limiting factor in the oxidation taking place at the enzyme.
Claims31
An enzyme-containing membrane comprising a semi-interpenetrating polymer network of fibrillated polytetrafluoroethylene and a silicon compound wherein the network is infiltrated with an enzyme.
A membrane system comprising:
- an outer membrane;
- and
- an inner membrane, wherein the inner membrane is an enzyme-containing membrane having a semi-interpenetrating polymer network of fibrillated polytetrafluoroethylene and a silicon compound, wherein the network is infiltrated with an enzyme.
A glucose sensor comprising:
- a membrane system having an outer membrane and an inner membrane, wherein the inner membrane is an enzyme-containing membrane which includes a semi-interpenetrating polymer network of fibrillated polytetrafluoroethylene and a silicon compound, wherein the network is infiltrated by an enzyme, and wherein the outer membrane restricts the flow of glucose into the inner membrane;
- an electrode which oxidizes hydrogen peroxide;
- and
- wherein the inner membrane is disposed between the outer membrane and the electrode.
Dependencies are inferred from the claim text.