Compositions and methods for intervertebral disc reformation
AssigneeThe Trustees of the University of Pennsylvania
InventorsJean Chin Chin Gan, Paul Ducheyne, Edward Vresilovic, Irving Shapiro
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Abstract
Methods of reforming degenerated intervertebral discs are provided in accordance with methods of the invention. Hybrid materials useful in methods of the present invention are also provided.
Claims17
A bioactive substrate comprising a porous polymer foam coated with sol gel bioactive material wherein said sol gel bioactive material penetrates the pores of said polymer foam and at least about 50% of the surface of said polymer foam, which includes the pores, is coated with said sol gel.
A hybrid material for reforming degenerated intervertebral disc tissue of a patient comprising a synthetic biodegradable substrate and cells extracted from intervertebral disc tissue, said cells comprising nucleus pulposus cells.
Dependencies are inferred from the claim text.