Epoxides, process for their preparation and their use for the preparation of perfuming ingredients
AssigneeFirmenich SA
InventorCharles Fehr
Life of this patent
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Abstract
Epoxides of formula ##STR1## having a cyclanic (1R) configuration, the group in position 2 being in a trans configuration and the epoxy group being in a cis configuration with respect to that in position 1 of the ring, and in which R represents a lower alkyl group and R.sup.1 represents a saturated or unsaturated, linear or branched hydrocarbon group having from 1 to 8 carbon atoms, are useful molecules for the preparation of very prized perfuming ingredients. A process for the preparation of the opoxides (I) is also described.
Claims10
Epoxide of formula ##STR27## Having a cyclanic (1R) configuration, the group in position 2 being in a trans configuration and the epoxy group being in a cis configuration with respect to that in position 1 of the ring, and in which R represents a lower alkyl group and R.sup.1 represents a saturated or unsaturated, linear or branched hydrocarbon group having from 1 to 8 carbon atoms.
(+)-Methyl (1R,2S,3R)-2,3-epoxy-2-pentyl-1-cyclcopentaneacetate.
A process for preparation of an epoxide of formula, ##STR28## having a cyclanic (1R) configurations the group in position 2 being in a trans configuration and the epoxy group being in a cis configuration with respect to that in position 1 of the ring, and in which R represents a lower alkyl group and R.sup.1 represents a saturated or unsaturated, linear or branched hydrocarbon group having from 1 to 8 carbon atoms, wherein an ester of formula ##STR29## having a cyclanic configuration (1R)-cis and in which the symbols R and R.sup.1 have the meaning indicated in formula (I), is reacted with a strong peracid in an inert organic solvent.
Epoxide of formula ##STR33## wherein the substituent groups epoxy and carboxy have a strictly cis configuration, R stands for a lower alkyl radical and R.sup.1 stands for a hydrocarbon group, saturated or unsaturated, linear or branched, having from 1 to 8 carbon atoms.
Dependencies are inferred from the claim text.