Psychosis protecting nucleic acid, peptides, compositions and method of use
OwnerArnold J. Friedhoff, Daryl A. Basham +1inventors
InventorsArnold J. Friedhoff, Daryl A. Basham, Jeannette C. Miller
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Abstract
Psychosis protecting (PP) nucleic acids and encoded PP peptides and related proteins, and antibodies, anti-idiotype antibodies, and fragments thereto, for treatment, diagnosis and/or research related to the protection from psychosis such as schizophrenia or related disorders, or symptoms thereof, and expression products, compositions and methods therefor, including treatment of schizophrenia and related disorders, as well as transgenic non-human mammals epxressing PP peptide or related protein encoding nucleic acids.
Claims27
An isolated nucleic acid molecule comprising at least 30 consecutive nucleotides from SEQ ID NO:3, SEQ ID NO:4, SEQ ID NO:5, or SEQ ID NO:9, or from the complementary strand of any one thereof.
An isolated nucleic acid molecule comprising at least 30 consecutive nucleotides from SEQ ID NO:3, SEQ ID NO:4, SEQ ID NO:5, or SEQ ID NO:9, or from the complementary strand of any one thereof, and further comprising a detectable label such that said molecule can be used as a detectable probe.
An isolated molecule comprising a human cDNA molecule which includes the sequence of SEQ ID NO:3, SEQ ID NO:4, SEQ ID NO:5, SEQ ID NO:6, or SEQ ID NO:9, or the complementary strand of any one thereof.
A vector comprising a nucleic acid molecule comprising at least 30 consecutive nucleotides from SEQ ID NO:3, SEQ ID NO:4, SEQ ID NO:5, or SEQ ID NO:9, or from the complementary strand of any one thereof.
An isolated nucleic acid molecule comprising at least 60 consecutive nucleotides from SEQ ID NO:6, or from the complementary strand thereof, and further comprising a detectable label such that said molecule can be used as a detectable probe.
A vector comprising a nucleic acid molecule comprising at least 60 consecutive nucleotides from SEQ ID NO:6, or from the complementary strand thereof.
A vector comprising a nucleic acid molecule comprising 60-100 consecutive nucleotides from SEQ ID NO:6, or from the complementary strand thereof.
Dependencies are inferred from the claim text.