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US 5,962,548 AGranted
Silicone hydrogel polymers
AssigneeJohnson & Johnson Vision Products, Inc.
InventorsDouglas G. Vanderlaan, Marcie Hargiss
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Abstract
A silicone hydrogel polymer prepared by curing a reaction mixture comprising a hydroxyalkylamine-functional silicone-containing monomer.
Claims19
A silicone hydrogel polymer prepared by curing a reaction mixture comprising a hydroxyalkylamine-functional silicone-containing monomer, comprising the following structure:
- ##STR8## wherein:
- n is 0 to 500 and m is 0 to 500 and (n+m)=10 to 500;
- R.sup.2, R.sup.4, R.sup.5, R.sup.6 and R.sup.7 are independently a monovalent alkyl, or aryl group, which may be further substituted with alcohol, ester, amine, ketone, carboxylic acid or ether groups, and
- R.sup.1, R.sup.3 and R.sup.8 are independently a monovalent alkyl, or aryl group, which may be further substituted with an alcohol, ester, amine, ketone, carboxylic acid or ether group;
- or have the following structure:
- ##STR9## with the proviso that at least one of R.sup.1, R.sup.3, and R.sup.8 are according to Structure II, wherein
- R.sup.9 is a divalent alkyl group;
- R.sup.10 and R.sup.11 are independently H, a monovalent alkyl or aryl group which may be further substituted with an alcohol, ester, amine, ketone, carboxylic acid or ether group, or have the following structure:
- ##STR10## where R.sup.14 is H, or a monovalent polymerizable group comprising acryloyl, methacryloyl, styryl, vinyl, allyl or N-vinyl lactam;
- R.sup.16 is H, a monovalent alkyl or aryl group which can be further substituted with alcohol, ester, amine, ketone, carboxylic acid or ether groups, or a polymerizable group comprising acrylate, methacrylite, styryl, vinyl, allyl or N-vinyl lactam;
- R.sup.12, R.sup.13 and R.sup.15 are independently H, a monovalent alkyl or aryl, which can be further substituted with alcohol, ester, amine, ketone, carboxylic acid or ether groups, or R.sup.12 and R.sup.15, or R.sup.15 and R.sup.13 can be bonded together to form a ring structure, with the proviso that at least one of the Structure II groups on the monomer comprise polymerizable groups.
8 more elements
A soft contact lens comprising a silicone hydrogel polymer prepared by curing a reaction mixture comprising a linear or branched, block or random, hydroxyalkylamine-functional silicone-containing monomer, comprising the following structure:
- ##STR14## wherein:
- n is 0 to 500 and m is 0 to 500 and (n+m)=10 to 500;
- R.sup.2, R.sup.4, R.sup.5, R.sup.6 and R.sup.7 are independently a monovalent alkyl, or aryl group, which may be further substituted with alcohol, ester, amine, ketone, carboxylic acid or ether groups, and
- R.sup.1, R.sup.3 and R.sup.8 are independently a monovalent alkyl, or aryl group, which may be further substituted with an alcohol, ester, amine, ketone, carboxylic acid or ether group, or have the following structure:
- ##STR15## with the proviso that at least one of R.sup.1, R.sup.3, and R.sup.8 are according to Structure II, wherein
- R.sup.9 is a divalent alkyl group such as --(CH.sub.2).sub.s -- where s is from 1 to 10;
- R.sup.10 and R.sup.11 are independently H, a monovalent alkyl or aryl group which may be further substituted with an alcohol, ester, amine, ketone, carboxylic acid or ether group, or has the following structure:
- ##STR16## where R.sup.14, is H, or a monovalent polymerizable group comprising acryloyl, methacryloyl, styryl, vinyl, allyl or N-vinyl lactam;
- R.sup.16 is either H, a monovalent alkyl or aryl group which can be further substituted with alcohol, ester, amine, ketone, carboxylic acid or ether groups, or a polymerizable group comprising acrylate, methacrylate, styryl, vinyl, allyl or N-vinyl lactam;
- R.sup.12, R.sup.13 and R.sup.15 are independently H, a monovalent alkyl or aryl, which can be further substituted with alcohol, ester, amine, ketone, carboxylic acid or ether groups, or R.sup.12 and R.sup.15, or R.sup.15 and R.sup.13 can be bonded together to form a ring structure, with the proviso that at least some of the Structure II groups on the monomer comprise polymerizable groups.
7 more elements
Dependencies are inferred from the claim text.