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AssigneeTristrata Technology, Inc.
InventorsRuey J. Yu, Eugene J. Van Scott
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Composition and method for enhancing therapeutic effects of topically applied agents are disclosed. The cosmetic or therapeutic composition may include one or more of cosmetic or pharmaceutical agents present in a total amount of from 0.01 to 40 percent and one or more of hydroxycarboxylic acids or related compounds present in a total amount of from 0.01 to 99 percent by weight of the total composition. The cosmetic and pharmaceutical agents may include but not limited to age spots, wrinkles and keratoses removing agents; vitamins; aloes; sun screens; tanning, depigmenting and shampooing agents; antiyeasts; antifungal, antibacterial and antiviral agents; topical bronchial dilators and topical cardiovascular agents; hormonal agents; vasodilators; retinoids and other dermatological agents. The hydroxycarboxylic acids and related compounds include organic alpha and beta hydroxycarboxylic acids, alpha and beta ketocarboxylic acids and salts thereof. Topical application of the cosmetic or therapeutic composition has been found to achieve a substantial increase in cosmetic or therapeutic effect of the active ingredient in humans and domesticated animals.
A composition comprising at least one hydroxycarboxylic acid or ketocarboxylic acid present in an enhancing effective amount and at least one agent other than a corticosteroid, said agent being selected from an antihistamine, an analgesic, an anesthetic and an antipruritic agent, wherein the hydroxycarboxylic acid or ketocarboxylic acid is present as a free acid, ester, lactone, pharmaceutically acceptable salt thereof, or an isomer selected from D, L and DL isomers.
A method of enhancing the therapeutic effect of a composition comprising at least one agent other than a corticosteroid, said agent being selected from the group consisting of an antihistamine, and analgesic, an anesthetic and an antipruritic agent in a pharmaceutically acceptable vehicle, comprising:
A method of alleviating symptoms associated with skin conditions and disorders selected from the group consisting of pain, inflammation and itching, comprising topically applying a therapeutically effective amount of a composition comprising at least one agent other than a corticosteroid, said agent being selected from the group consisting of an antihistamine, and analgesic, an anesthetic and an antipruritic agent in a pharmaceutically acceptable vehicle, comprising:
Dependencies are inferred from the claim text.