Screening methods for cytokine inhibitors
AssigneeAdolor Corporation
InventorVivian Mak
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Abstract
The present invention provides a number of screening methods for evaluatiing compounds capable of suppressing cytokine production either in vitro or in vivo. The methods generally involve stimulating the production of a cytokine in a cell, exposing a portion of the cells to a putative cytokine modulating agent and determining subsequent levels of cytokine production in the cells. Additionally, the present invention provides certain compounds identified by this method.
Claims5
A composition formulated for topical administration, comprising loperamide in a non-aqueous-based vehicle suitable for topical application to the skin.
A composition formulated for topical administration, comprising loperamide in a vehicle suitable for topical application to the skin, wherein the composition is formulated as a gel.
A composition formulated for topical administration, comprising loperamide in a vehicle suitable for topical application to the skin, wherein the composition is formulated as a lotion.
A composition formulated for topical administration, comprising loperamide in a vehicle suitable for topical application to the skin, wherein the composition is formulated as a cream.
Dependencies are inferred from the claim text.