7-(4-aminomethyl-3-methyloxyiminopyrrolidin-1-yl)-1- cyclopropyl-6-fluoro-4-oxo-1, 4-dihydro-1, 8-naphthyridine-3-carboxylic acid and the process for the preparation thereof
AssigneeLG Chemical Ltd.
InventorsChang Yong Hong, Young Kwan Kim, Se Ho Kim, Jay Hyok Chang, Hoon Choi, Do Hyun Nam, Ae Ri Kim, Jin Hwa Lee, Ki Sook Park
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Abstract
The present invention relates to a novel quinolone compound having an excellent antibacterial activity. More specifically, the present invention relates to 7-(4-aminomethyl-3-methyloxyiminopyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-4 -oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid represent by the following formula: ##STR1## or its isomer.
Claims12
A method for prophylaxis or treatment of bacterial infections in a warm blooded animal, comprising administering an effective amount of the compound 7-(4-aminomethyl-3-methyloxyiminopyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-4 -oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid of the following formula:
- ##STR269## or a pharmaceutically acceptable non-toxic salt, physiologically hydrolyzable ester, or isomer thereof.
A method for prophylaxis or treatment of bacterial infections in a warm blooded animal, comprising administering 7-(4-aminomethyl-3-methyloxyiminopyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-4 -oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid methanesulfonate or a hydrate thereof of the following formula:
- ##STR270## in which n is 0, 1, 1.5, 2.5, 3, 3.5 or 4, or an isomer thereof.
Dependencies are inferred from the claim text.