Method of making polymers having specific properties
AssigneeArQule, Inc.
InventorJoseph C. Hogan, Jr.
Life of this patent
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Abstract
A method of making a polymer having specific physiochemical properties by forming a first module having a structure which includes at least two structural diversity elements suitable to impart a desired physical property to a polymer which is made from said monomer; and reacting one or more modules to form a polymer having specific physiochemical properties. The base module can be formed by reacting a first compound having at least one structural diversity element and a first reactive group, with a second compound having at least one structural diversity element and a second reactive group, wherein the first and second groups combine by an addition reaction. Specifically, an aminimide compound, an oxazolone compound or derivatives thereof are useful as base modules in the invention.
Claims24
A method of making a polymer having specific physiochemical properties which comprises:
- forming modules having a structure which includes at least one orthogonal reactivity element for reaction with another module and two structural diversity elements which impart a desired physical property to a polymer which is made from joining together at least two modules;
- and
- reacting the reactivity element of a first module with the reactivity element of a second module by a stepwise addition reaction to effect a controlled polymerization, whereby the modules are joined together to form a polymer having specific physiochemical properties and the reacting step is carried to completion before any additional reacting steps are undertaken to join additional modules to the polymer.
A method of making a polymer having specific physiochemical properties including a particular water solubility which comprises:
- forming a first module having at least one orthogonal reactivity element for reaction with another module, at least two structural diversity elements, and at least one hydrophobic moiety;
- forming a second module having at least one orthogonal reactivity element for reaction with another module, at least two structural diversity elements, and at least one hydrophilic moiety;
- and
- joining together the first and second modules by reacting the reactivity element of the first module with the reactivity element of the second module by a stepwise addition reaction to effect a controlled polymerization, whereby the modules are joined together to form a polymer having specific physiochemical properties including a specific molecular weight, a specific length and a particular water solubility.
A polymer comprising at least three connected modules wherein the modules are connected by an addition reaction, and at least one module has a structure which includes at least two structural diversity elements.
A method of making a polymer having specific physiochemical properties including a particular water solubility which comprises:
- forming a first module having a hydrophobic moiety attached thereto, at least one orthogonal reactivity element for reaction with another module and one or more points of attachment for structural diversity elements;
- forming a second module having a hydrophilic moiety attached thereto, at least one orthogonal reactivity element for reaction with another module and one or more points of attachment for structural diversity elements;
- and
- joining together the first and second modules by reacting the reactivity element of the first module with the reactivity element of the second module by a stepwise addition reaction to control the addition of each module to a developing polymer chain to form a polymer having specific physiochemical properties including a specific molecular weight, a specific length and a particular water solubility.
Dependencies are inferred from the claim text.