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US 5,962,283 AGranted
Transminases and amnotransferases
AssigneeDiversa Corporation
InventorsPatrick V. Warren, Ronald V. Swanson
Life of this patent
Estimating the term…
Abstract
Thermostable transaminase and aminotransferase enzymes derived from various ammonifex, aquifex and pyrobaculum organisms are disclosed. The enzymes are produced from native or recombinant host cells and can be utilized in the pharmaceutical, agricultural and other industries.
Claims10
An isolated polynucleotide selected from the group consisting of:
- a) a polynucleotide encoding SEQ ID NOs:
- 36 or 40;
- and
- b) a nucleic acid sequence fully complementary to a).
1 more element
An enzyme selected from the group consisting of an enzyme comprising the amino acid sequence as set forth in SEQ ID NOS:
- 36 and 40.
A method for transferring an amino group from an amino acid to an .alpha.-keto acid comprising:
- contacting an amino acid in the presence of an .alpha.-keto acid with an enzyme selected from the group consisting of an enzyme having the amino acid sequence set forth in SEQ ID NOS:
- 36 and 40.
Dependencies are inferred from the claim text.