Methods for producing antibodies which specifically bind to interleukin-9 receptor
AssigneeLudwig Institute for Cancer Research
InventorsJean-Christophe Renauld, Catherine Druez, Jacques Van Snick
Life of this patent
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Abstract
The invention describes nucleic acid sequences which code for the interleukin 9 receptor (IL9-R) molecule. These sequences may be used as probes to identify cells expressing the molecule, and as agents to transfect recipient cells.
Claims9
A process for producing an antibody which specifically binds to interleukin 9 receptor comprising immunizing a subject animal with a cell line transfected with a nucleic acid molecule which codes for interleukin-9 receptor in an amount sufficient to generate antibodies which specifically bind to interleukin-9 receptor, and isolating said antibodies from said animal .
A method for producing an antibody which specifically binds to interleukin 9 receptor comprising immunizing a non-human animal with a non-glycosylated interleukin 9 receptor in an amount sufficient to generate an antibody specific for interleukin 9 receptor, and purifying said antibody.
Monoclonal antibody which specifically binds to an interleukin-9 receptor.
A method for producing an isolated monoclonal antibody which specifically binds to interleukin 9 receptor comprising immunizing a non-human animal with a protein having an amino acid sequence selected from the group consisting of SEQ ID NO.:
- 7, 8, 9, 10, 11, and 12, in an amount sufficient to generate a monoclonal antibody specific for interleukin 9 receptor.
Dependencies are inferred from the claim text.