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AssigneeHeska Corporation
InventorsRobert B. Grieve, Keith E. Rushlow, Shirley Wu Hunter, Glenn R. Frank, Gary L. Stiegler
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The present invention relates to flea serine protease and aminopeptidase proteins; to flea serine protease and aminopeptidase nucleic acid molecules, including those that encode such proteins; to antibodies raised against such proteins; and to compounds that inhibit flea serine protease and/or aminopeptidase activities. The present invention also includes methods to obtain such proteins, nucleic acid molecules, antibodies, and inhibitors. Also included in the present invention are therapeutic compositions comprising such proteins, nucleic acid molecules, antibodies, and/or inhibitors as well as the use of such therapeutic compositions to protect a host animal from flea infestation.
An isolated flea aminopeptidase nucleic acid molecule comprising a flea nucleic acid sequence selected from the group consisting of:
A method to produce a flea aminopeptidase protein, said method comprising culturing a cell capable of expressing said protein, said protein being encoded by a nucleic acid molecule comprising a nucleic acid sequence selected from the group consisting of:
Dependencies are inferred from the claim text.