Combined pharmaceutical estrogen-androgen-progestin oral contraceptive
AssigneeWake Forest Universtiy
InventorsClaude L. Hughes, Jr., Manuel J. Jayo
Life of this patent
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Abstract
Disclosed are methods and compositions for oral contraception and hormonal therapy. Certain compositions and methods of the invention contain androgens, and preferably methyltestosterone to be combined with estrogen and progestin compositions in a hormonal component of a pharmaceutical composition.
Claims94
A method of producing a desired estrogen to androgen balance in a female, comprising administering to the female a pharmaceutical composition comprising a hormonal component, wherein the hormones in the hormonal component are an estrogen, a progestin and an androgen.
A method of preventing pregnancy in a premenopausal female comprising administering to the female a pharmaceutical composition comprising a hormonal component, wherein the hormones in the hormonal component are an estrogen, a progestin and an androgen.
A method of increasing the level of free testosterone in the serum of a female comprising administering to the female a pharmaceutical composition comprising a hormonal component, wherein the hormones in the hormonal component are an estrogen, a progestin and an androgen.
A method of replacing the natural estrogen to androgen balance in a female with a deficiency or imbalance of ovarian secretions comprising administering to the female a pharmaceutical composition comprising a hormonal component, wherein the hormones in the hormonal component are an estrogen, a progestin and an androgen.
A method of replacing the natural estrogen to androgen balance in a female in need of estrogen therapy, wherein the method comprises administering to the female a pharmaceutical composition comprising a hormonal component, wherein the hormones in the hormonal component are an estrogen, a progestin and an androgen.
Dependencies are inferred from the claim text.