Method of treating the skin with organic acids in anhydrous microsphere delivery systems
AssigneeAvon Products, Inc.
InventorsErnest S. Curtis, Robert Kalafsky, Elinor R. Kaplan
Life of this patent
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Abstract
There is provided a method of treating skin with a therapeutic, water-soluble organic acid. There is also provided an anhydrous composition containing the water-soluble organic acid is encapsulated into hydrophobic microspheres through which the organic acid can elute in the presence of water is applied to the skin. The composition is wet with water immediately prior to, or after the composition is applied to the skin.
Claims20
A therapeutic composition comprising:
- an anhydrous vehicle selected from the group consisting of powder, lotion, solid, cream and gel;
- at least one microsphere;
- and
- from about 20 wt %.% to about 30 wt. % of a water-soluble organic acid entrapped within said at least one microsphere
- wherein said at least one microsphere is formed of a non-polar copolymer of a carbamate and an acrylate, and wherein the addition of water to the composition facilitates the elution of said water-soluble organic acid from within said at least one microsphere to without said at least one microsphere.
A method of treating a skin or hair condition with a therapeutic, water-soluble organic acid, said method comprising:
- applying to the skin or hair an anhydrous composition that includes a water-soluble organic acid encapsulated in one or more microspheres through which said organic acid will elute in the presence of water;
- and
- wetting said composition with water immediately prior to, or after applying said composition to the skin or hair,
- wherein said skin or hair condition is selected from the group consisting of dry skin, ichthyosis, palmar and plantar hyperkeratoses, dandruff, lichen simplex chronicus, Dariers disease, keratoses, lentigines, age spots, melasmas, blemished skin, acne, psoriasis, eczema, pruritis, inflammatory dermatoses, striae distensae, warts, calluses, ingrown hair, folliculitis, Pseudofolliculitis barbae, photoaging, fine wrinkles, irregular pigmentation, sallowness, loss of skin resilience and loss of elasticity, and
- wherein said microsphere is formed of a non-polar copolymer of a carbamate and an acrylate.
A method for preparing a topical composition useful for delivering a water-soluble organic acid to the skin using an anhydrous vehicle, said method comprising:
- encapsulating said water-soluble organic acid into one or more microsphere formed of a non-polar copolymer of a carbamate and an acrylate, and
- incorporating said one or more microspheres into an anhydrous vehicle to form an organic acid microsphere composition, and
- applying said organic acid microsphere composition to the skin;
- wherein the presence of water activates said water-soluble organic acid microsphere composition causing said organic acid to elute from said one or more microspheres.
Dependencies are inferred from the claim text.