Topical medicament for use in treatment of anorectal inflammation

#1. Field of the Invention

#The present invention pertains to the field of topical ointments or creams that may be used to sooth pain, swelling, and itching that is associated with anorectal inflammation caused by hemorrhoids and the like. More specifically, the topical ointment contains a vasoconstrictor in combination with a plurality of antibacterial agents.

#2. Statement of the Problem

#The following non-limiting examples are used to present the most preferred product formulation, as well as evidence of biological utility of this formulation in actual use on human patients.

#The following ingredients were weighed out and blended to substantial homogeneity in a stable emulsion to form a medicinal cream. This formulation is particularly preferred for its ability to adhere to inflamed anorectal tissues while providing multiple benefits to the tissues according to the principles discussed above.

#TABLE 1 ______________________________________ INGREDIENTS Ingredient Weight Percent Purpose ______________________________________ Snow White 50 Active agent for Petrolatum soothing and protection of inflamed tissues; mild desiccant Phelylephrine 0.25 Active ingredient hydrochloride vasoconstrictor Purified water 19 Solubilizing agent for Phenylephrine hydrochloride; thinner for emulsified base Lanolin 16.5 Emulsifier Beeswax 7.5 Emulsifier, thickening agent Squalene 2.5 Emulsifier, bactericide, carrier of lipid-soluble materials, surface active agent, penetrant Tocopherol acetate 1 Preservative, vitamin E nutritional benefit Sodium borate 0.94 Emulsifier Lanolin alcohol 0.5 Emulsifier Methyl salicylate 0.25 Fragrance, counterirritant Sorbitan sesquioleate 0.25 Emulsifier 8-hydroxyquinoline 0.22 Odor neutralizer, antimicrobial agent Methylparaben 0.25 Preservative Propylparaben 0.1 Preservative Trisodium EDTA 0.05 Preservative ______________________________________