Melanoquaternary compounds and their use as hair dyes and for skin treatment
AssigneeBristol-Myers Squibb Company
InventorsGottfried Wenke, Giuseppe Prota
Life of this patent
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Abstract
Water soluble, cationic products useful as hair colorants or for the treatment of skin which are esters or amides formed by reaction of melanin and a quaternary salt containing a reactive amino or hydroxyl group, as well as compositions containing them and methods of using such products to color hair or treat skin are described.
Claims30
A water soluble cationic compound that is an amide or ester obtained by reacting a melanin with a quaternary salt having at least one reactive amino or hydroxyl group.
A composition comprising in an amount effective to color hair or treat skin, a compound having the formula:
- ##STR3## wherein:
- M is a melanin residue,
- Y is --O-- or NH,
- R, R.sub.1, R.sub.2 and R.sub.3 are groups that in combination one with the other quaternize the nitrogen to which they and R are bonded,
- m is the number of derivatized carboxyl groups in the melanin residue, and
- X is an anion, and
- a cosmetically acceptable vehicle.
A method of coloring hair (or skin) which comprises contacting hair (or skin) with an effective hair dyeing (or skin treating) amount of a compound of the formula:
- ##STR4## wherein:
- M is a melanin residue,
- Y is --O-- or NH,
- R, R.sub.1, R.sub.2 and R.sub.3 are groups that in combination one with the other quaternize the nitrogen to which they and R are bonded,
- m is the number of derivatized carboxyl groups in the melanin residue, and
- X is an anion.
A composition comprising a water soluble cationic compound that is an amide or ester obtained by reacting a melanin with a quaternary salt having at least one reactive amino or hydroxyl group, said cationic compound being present in the composition in an amount effective to dye hair or treat skin, and a cosmetically acceptable vehicle.
Dependencies are inferred from the claim text.