Monoclonal antibodies to CD40 ligand, pharmaceutical composition comprising the same and hybridomas producing the same
AssigneeImmunex Corporation
InventorsRichard J. Armitage, William C. Fanslow, Melanie K. Spriggs
Life of this patent
Estimating the term…
Abstract
There is disclosed a polypeptide (CD40-L) and DNA sequences, vectors and transformed host cells useful in providing CD40-L polypeptides. More particularly, this invention provides isolated human and murine CD40-L polypeptides that bind to the extracellular binding region of a CD40 receptor.
Claims8
An anti-human CD40L monoclonal antibody selected from the group consisting of M90 secreted by hybridoma hCD40L-M90 designated by ATCC Accession No. HB-12055, and M91 secreted by hybridoma hCD40L-M91 designated by ATTC Accession No. HB-12056.
A hybridoma hCD40L-M90 designated by ATCC Accession No. HB-12055.
A hybridoma hCD40L-M91 designated by ATCC Accession No. HB-12056.
Dependencies are inferred from the claim text.