Device for aerosolized delivery of peptide drugs

A peptide drug delivery device, comprising:

• a channel having a first opening into which air can be inhaled, a second opening from which a patient can withdraw air and a third opening positioned between the first and second openings;
• a disposable, dual compartment container, comprising;
• a first compartment having therein dry peptide drug, the first compartment having an opening therein which is covered by a flexible porous membrane with pores having a diameter of about 0.25 micron to about 6 microns, the membrane positioned at the third opening of the channel;
• and
• a second compartment having a flowable liquid therein connected to and in fluid connection with the first compartment, the fluid connection being interrupted by a membrane which is ruptured by the application of pressure;
• a means for applying force to the dual compartment container such that fluid in the second container is forced into the first container and out of the porous membrane;
• wherein the device is a hand-held self-contained device having a total weight of 1 kilogram or less.