Method of relieving inflammation by using 5-alkylsulfonylsalicylanilides
AssigneesThe Research Foundation of State University of New York, Therex Technologies, Inc.
InventorsRichard T. Evans, Robert A. Coburn, Robert A. Genco, Joseph A. Dunn
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Abstract
A method of treating inflammation in a mammal, which comprises contacting the affected area with an amount sufficient to ameliorate the inflammatory condition, of a compound of the following formula ##STR1## in a pharmaceutically acceptable carrier containing a detergent, where Z is a substituted phenyl, R is a substituted or unsubstituted alkylsulfonyl group from 1 to 20 carbon atoms and X is --CN, --NO.sub.2, --H, halogen, lower alkyl or lower haloalkyl radical.
Claims33
A method of treating inflammation in a mammal, which comprises contacting the affected area with an amount sufficient to ameliorate the inflammatory condition, of a compound of the following formula ##STR21## in a pharmaceutically acceptable carrier, said carrier comprising a detergent, wherein Z is a substituted phenyl ring, wherein the substitution on Z is selected from the group consisting of --CF.sub.3, --CN and --NO.sub.2, wherein R is an alkylsulfonyl group of 1 to 20 carbon atoms, and X is selected from the group consisting of --CN, --NO.sub.2, --H, halogen, lower alkyl and lower haloalkyl.
Dependencies are inferred from the claim text.