Potentiation of serotonin response
AssigneeEli Lilly and Company
InventorDavid T Wong
Life of this patent
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Abstract
The availability of serotonin, norepinephrine and dopamine in the brain is increased by administering a serotonin reuptake inhibitor with a serotonin 1A antagonist and L-tryptophan or 5-hydroxy-L-tryptophan.
Claims14
A method for potentiating the action of a first component which is a serotonin reuptake inhibitor in increasing the availability of serotonin, norepinephrine and dopamine in the brain, comprising administering a first component in combination with a second component which is a serotonin 1A receptor antagonist and with a third component which is L-tryptophan or 5-hydroxy-L-tryptophan or a pharmaceutically acceptable salt thereof.
A pharmaceutical composition which comprises a first component which is a serotonin reuptake inhibitor, a second component which is a serotonin 1A receptor antagonist, and a third component which is L-tryptophan or 5-hydroxy-L-tryptophan or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.