Treatment of burns, cuts, and abrasions of the skin
AssigneeNortrade Medical, Inc.
InventorMarc S. Jenson
Life of this patent
Estimating the term…
Abstract
A burn wound treatment system comprising a water-tight, sealed envelop containing a sterile, flexible, non-adherent dressing material and a sterile, stable, water soluble thixotropic gel. The gel of the present invention comprises tea tree oil and has the surprising capability of significantly lowering of the intradermal temperature of a burn wound upon topical application. The gel also inhibits infection and promotes healing of burn, chronic and acute wounds. The present invention preferably further comprises a waterproof barrier to be positioned and secured over the sterile dressing to protect against contamination and to prevent moisture loss.
Claims6
A method of promoting healing and epithelialization of a wound on the skin of a warm-blooded animal comprising applying a composition comprising a stable, water-soluble, biocompatible, thixotropic hydrogel comprising about about 0.01 to 20% by weight of tea tree oil, about 0.0003 to 0.5% by weight of chlorobutanol, about 0.0003 to 0.5% by weight of triclosan, about 0.01 to 1% by weight of polyoxyethylene alkylphenol, about 0.1 to 10% by weight of carboxymethylcellulose, about 0.025 to 0.5% by weight of ethanol, about 0.1 to 1.5% by weight of propylene glycol, an amount of an acid, base, or buffer sufficient to adjust the pH to about 5.5 to 7.0, and the rest water, to the wound for at least about 20 minutes.
A method of making a topical wound treatment composition comprising the steps of:
- (a) dissolving about 0.003 to 0.5 parts by weight of chlorobutanol in about 0.025 to 0.5 parts by weight of ethanol;
- (b) adding about 0.01 to 1 parts by weight of polyoxyethylene alkylphenol to the chlorobutanol and ethanol, followed by adding about 0.003 to 0.5 parts by weight of triclosan and about 0.1 to 10 parts by weight of carboxymethylcellullose;
- (c) then adding about 0.1 to 1.5 parts by weight of propylene glycol and stirring thoroughly;
- (d) next adding a portion of about 78 to 98.9 parts by weight of water and mixing thoroughly to result in a concentrated gen base;
- (e) placing the remaining portion of the water in a separate container and adding the concentrated gel base thereto with agitation until the resulting mixture is smooth;
- (f) mixing about 0.01 to 20 parts by weight of tea tree oil with the smooth mixture;
- and
- (g) adding an effective amount of an acid base, or buffer to the mixture to obtain a pH of 5.5 to 7.0 and mixing until a smooth thixotropic gel is formed.
Dependencies are inferred from the claim text.