Interleukin-6 splice variant
AssigneeHuman Genome Sciences, Inc.
InventorsSteven Ruben, Haodong Li, Mark D. Adams
Life of this patent
Estimating the term…
Abstract
Polynucleotides which encode the polypeptide IL-6SV, as well as such polypeptides, antibodies and antagonist inhibitors against the polypeptide and the use of the polypeptide as a pharmaceutical for treating cancer, auto-immune diseases, platelet reducing conditions, anemias, bone marrow and organ transplantation.
Claims12
An isolated polypeptide comprising the amino acid sequence shown in SEQ ID NO:2.
An isolated polypeptide comprising the amino acid sequence of the polypeptide encoded by the human cDNA contained in ATCC Deposit No. 75697.
An isolated polypeptide produced by a process comprising:
- (a) culturing a host cell comprising a polynucleotide which encodes a polypeptide comprising the amino acid sequence shown in SEQ ID NO:2, wherein said polynucleotide is linked to a heterologous regulatory element that controls gene expression;
- and
- (b) recovering said polypeptide.
An isolated polypeptide produced by a process comprising:
- (a) culturing a host cell comprising a polynucleotide which encodes the polypeptide encoded by the human cDNA contained in ATCC Deposit No. 75697, wherein said polynucleotide is linked to a heterologous regulatory element that controls gene expression;
- and
- (b) recovering said polypeptide.
Dependencies are inferred from the claim text.