4,4-dihydroxy-5-pyrazolinones and cosmetic/dermatological compositions comprised thereof

A 4,4-dihydroxy-5-pyrazolinone compound having the structural formula (I):

• ##STR14## in which R.sub.1 is a hydrogen atom;
• a linear or branched C.sub.1 -C.sub.18 alkyl radical optionally substituted with a hydroxyl (OH), sulfonyl (SO.sub.3 H), carboxyl (COOH), C.sub.2 -C.sub.4 hydroxyalkyl or cyclopentyl radical;
• a cyclohexyl or cyclopentyl radical;
• a radical:
• ##STR15## wherein m is equal to 1, 2 or 3, n is equal to 1, 2 or 3, X is a hydrogen atom or a methyl radical, and Y is a methyl, hydroxyl or linear or branched C.sub.1 -C.sub.5 alkoxy radical;
• a radical --(CH.sub.2).sub.p --OR' wherein R' is a substituted or unsubstituted phenyl or naphthyl radical and p is equal to 1 or 2;
• a radical --(CH.sub.2).sub.q --R" wherein q is equal to 1, 2 or 3 and R" is a phenyl radical which is unsubstituted or substituted with not more than two radicals selected from among methyl, trifluoromethyl, methoxy and sulfonyl radicals, a naphthyl radical, a thienyl radical, a furyl radical, a pyridyl radical or a
• piperidyl radical, a radical:
• ##STR16## a radical:
• ##STR17## or a radical:
• ##STR18## a phenyl radical;
• a phenyl radical substituted with one or two nitro radicals;
• a phenyl radical substituted with a phenyl radical substituted with one or two nitro radicals;
• a phenyl radical substituted with one to five radicals selected from among --COOH, --CH.sub.2 COOH, --Cl, --Br, --F, --OH, --SO.sub.3 H, --CH.sub.2 OH, --OCF.sub.3, --CF.sub.3, --SO.sub.2 CH.sub.3, --SO.sub.2 NH.sub.2, --SO.sub.2 NHC.sub.2 H.sub.5, --SO.sub.2 NHCH.sub.2 CH.sub.2 OH, --CON(CH.sub.3).sub.2, --CON(C.sub.2 H.sub.5).sub.2, --CH.sub.2 N(CH.sub.3).sub.2, --.sub.CH2N (C2H.sub.5).sub.2, --NHCOCH.sub.3, --NHCOC.sub.2 H.sub.5, a C.sub.1 -C.sub.8 alkyl radical or a radical --ZR.sub.3 wherein Z is an oxygen or sulfur atom and R.sub.3 is a hydrogen atom or a linear or branched C.sub.1 -C.sub.18 alkyl radical;
• a naphthyl radical optionally substituted with an --SO.sub.3 H radical;
• a benzyl radical;
• a benzyl radical substituted with a --COOH, --OCH.sub.3 or --SO.sub.3 H radical;
• a pyridyl radical;
• a pyrimidinyl radical;
• a pyrazinyl radical;
• a triazinyl radical;
• a benzotriazolyl radical;
• a benzimidazolyl radical;
• a thienyl radical;
• an imidazolyl radical;
• a thiazolyl radical;
• a 1,2,4-triazolyl radical;
• an indazolyl radical;
• an indolyl radical, a quinolyl radical or an isoquinolyl radical;
• and R.sub.2 is a hydrogen atom;
• a linear or branched C.sub.1 -C.sub.18 alkyl radical optionally substituted with one or more hydroxyl radicals or C.sub.1 -C.sub.4 alkoxy radical;
• or a linear or branched C.sub.3 -C.sub.18 alkenyl radical optionally substituted with one or more hydroxyl radicals or C.sub.1 -C.sub.4 alkoxy radicals;
• a phenyl radical;
• a phenyl radical substituted with a halogen atom, a nitro radical or a trifluoromethyl radical;
• a phenyl radical substituted with not more than three radicals selected from among C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 dialkylamino and C.sub.1 -C.sub.2 alkylthio radicals;
• a benzyl radical;
• a benzyl radical substituted with a halogen atom, a C.sub.1 -C.sub.4 alkyl radical, a C.sub.1 -C.sub.4 alkoxy radical, a trifluoromethyl radical or a C.sub.1 -C.sub.4 dialkylamino radical;
• a radical --(CH.sub.2).sub.r --R.sub.4 wherein r is equal to 1, 2 or 3 and R.sub.4 is selected from among an --SO.sub.3 H radical, a C.sub.1 -C.sub.2 alkylthio radical or a benzylthio radical;
• a methoxycarbonyl or ethoxycarbonyl radical;
• a phenyl radical;
• a C.sub.1 -C.sub.4 alkoxy radical or a phenoxy radical optionally substituted with one or more halogen atoms;
• a C.sub.1 -C.sub.4 alkoxy radical;
• a phenoxy radical optionally substituted with one or more halogen atoms;
• a trifluoromethyl radical;
• an acetamido radical;
• a C.sub.1 -C.sub.4 dialkylamino radical;
• a carboxyl radical;
• a methoxycarbonyl radical;
• an ethoxycarbonyl radical;
• a radical --NH--CO--R.sub.5 wherein R.sub.5 is a linear or branched C.sub.1 -C.sub.18 alkyl radical or a C.sub.3 -C.sub.18 alkenyl radical;
• a thienyl radical;
• a furyl radical;
• a pyridyl radical or a pyrazolyl radical;
• or a halogen atom.