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US 5,955,028 AGranted
Analytical system and method
AssigneeCaliper Technologies Corp.
InventorCalvin Y. H. Chow
Life of this patent
Estimating the term…
Abstract
An analytical or preparatory system comprised as a base unit, an adapter, and a substrate. The adapter is attached to an attachment region on the base unit, and the substrate is attached to an attachment region on the adapter. The adapter permits the base unit to be interfaced with a wide variety of different substrates to perform chemical and biological analytical analyses and preparatory procedures.
Claims15
An analytical system comprising:
- a sample substrate having a plurality of mesoscale channels disposed therein, the plurality of channels connecting a plurality of reservoirs, each of the plurality of channels having at least one cross-sectional dimension between about 0.1 and 500 .mu.m;
- a base unit comprising an electrical power supply;
- a sample substrate interface array attached to the base unit and comprising:
- a sample substrate attachment region including a plurality of electrical connectors disposed thereon, the electrical connectors being electrically coupled to the electrical power supply and being positioned within the substrate attachment region to provide electrical connection between the plurality of reservoirs and the electrical power supply when the substrate is placed, in the substrate attachment region wherein the electrical connectors comprise pin electrodes disposed on the interface array, the pin electrodes being positioned to directly engage fluids present in the reservoirs;
- and
- an energy emission detector disposed in the base unit and positioned to detect energy emitted from at least one of the channels disposed in the sample substrate, when the sample substrate is placed in the sample substrate attachment region.
3 more elements
An analytical system comprising:
- a sample substrate having a plurality of mesoscale channels disposed therein, the plurality of channels connecting a plurality of reservoirs, each of the plurality of channels having at least one cross-sectional dimension between about 0.1 and 500 .mu.m;
- a base unit comprising an electrical power supply;
- a sample substrate interface array attached to the base unit and comprising:
- a sample substrate attachment region including a plurality of electrical connectors disposed thereon, the electrical connectors being electrically coupled to the electrical power supply and being positioned within the substrate attachment region to provide electrical connection between the plurality of reservoirs and the electrical power supply when the substrate is placed in the substrate attachment region, wherein the electrical connectors on the sample attachment region comprise electrical contacts that are positioned to establish electrical contact with a plurality of corresponding electrical contacts on the microfluidic device when the microfluidic device is placed in the substrate attachment region, the electrical contacts on the microfluidic device providing an electrical connection to the plurality of reservoirs;
- and
- an energy emission detector disposed in the base unit and positioned to detect energy emitted from at least one of the channels disposed in the sample substrate, when the sample substrate is placed in the sample substrate attachment region.
3 more elements
Dependencies are inferred from the claim text.