Long-chain alcohols, alkanes, fatty acids and amides in the treatment of burns and viral inhibition

A composition consisting of 10% w/w stearic acid, 5% w/w sucrose stearate, 8% w/w mineral oil NF, 5% w/w propylene glycol USP, 2.7% w/w benzyl alcohol NF and 69.3% purified water USP.

A method of treatment comprising administering to a mammal in need thereof an effective amount of a composition to prevent or treat viral infection, wherein said composition comprises a nonionic surfactant and an active ingredient in a ratio of about 1:1 (w:w) to about 10:1 (w:w), combined in a pharmaceutically acceptable diluent or carrier, wherein the nonionic surfactant is a block polymer having a molecular weight of about 1,000 to about 25,000, an octoxynol or deoxycholate, and wherein the active ingredient is stearyl alcohol, erucyl alcohol, brassidyl alcohol, n-docosane, n-docosanoic acid, erucamide, stearic acid or mixtures thereof.

A method of treatment comprising administering an effective amount of a composition to a mammal in need thereof to relieve skin or membrane inflammation, wherein said composition comprises a nonionic surfactant and an active ingredient in a ratio of about 1:1 (w:w) to about 10:1 (w:w), combined in a pharmaceutically acceptable diluent or carrier, wherein the nonionic surfactant is a block polymer having a molecular weight of about 1,000 to about 25,000, an octoxynol or deoxycholate, and wherein the active ingredient is stearyl alcohol, erucyl alcohol, brassidyl alcohol, n-docosane, n-docosanoic acid, erucamide, stearic acid or mixtures thereof.

A method of treatment comprising administering an effective amount of a composition to a mammal in need thereof to inhibit cell growth or proliferation, wherein said composition comprises a nonionic surfactant and n-docosanoic acid in a ratio of about 5:1 (w:w), and wherein said nonionic surfactant is a block polymer of ethylene oxide and propylene oxide, having a molecular weight of about 8,400.

A method of treatment comprising administering an effective amount of a composition to a mammal in need thereof to treat a burn, wherein said composition comprises a nonionic surfactant and an active ingredient, comprising a long chain fatty alcohol or fatty acid, in a ratio of surfactant to active ingredient of about 1:1 (w:w) to about 10:1 (w:w), wherein said surfactant and active ingredient are combined in a pharmaceutically acceptable diluent or carrier.

A composition comprising a nonionic surfactant and an active ingredient in a ratio of about 1:1 (w:w) to about 10:1 (w:w), combined in a pharmaceutically acceptable diluent or carrier, wherein said nonionic surfactant is octoxynol-9, octoxynol-10 or a combination thereof, and wherein said active ingredient is selected from the group consisting of stearyl alcohol, erucyl alcohol, brassidyl alcohol, arachidyl alcohol, n-docosanol, n-docosane, n-docosanoic acid, erucamide, stearic acid, and a mixture thereof.

A composition comprising a nonionic surfactant and an active ingredient in a ratio of about 4:1 (w:w) to about 10:1 (w:w), combined in a pharmaceutically acceptable diluent or carrier, wherein said active ingredient is stearic acid.

A composition comprising a nonionic surfactant and stearic acid in a ratio of about 1:1 (w:w) to about 10:1 (w:w), combined in a pharmaceutically acceptable diluent or carrier, wherein the stearic acid is suspended in the nonionic surfactant.

A method of treatment comprising administering an effective amount of a composition to a mammal in need thereof to relieve skin or membrane inflammation, wherein said composition comprises a nonionic surfactant, a sugar-based stearate and stearic acid, wherein the stearic acid comprises about 5% to about 20% (w/w) of said composition.