Methods for preparing biopolymer foams
AssigneeTissue Engineering, Inc.
InventorsEugene Bell, Timothy W. Fofonoff
Life of this patent
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Abstract
A biopolymer solution is polymerized to form a gel which is freeze-dried and crosslinked with ultraviolet radiation to form a biopolymer foam. The foam is filled with a collagen solution and the combination is freeze-dried or the foam is filled with a collagen solution containing extracellular matrix particulates and that combination is freeze-dried, thereby forming a foam to which extracellular matrix particulates are attached.
Claims26
A method for preparing a biopolymer foam, comprising:
- forming a biopolymer solution;
- crosslinking the biopolymer in the biopolymer solution without the use of crosslinking chemicals;
- and
- freeze-drying the biopolymer solution to form a biopolymer foam.
A method for preparing a biopolymer foam, comprising
- forming a biopolymer solution;
- polymerizing the biopolymer in the biopolymer solution, thereby forming a biopolymer lattice;
- crosslinking the biopolymer lattice without the use of crosslinking chemicals;
- and
- freeze-drying the biopolymer lattice to form a biopolymer foam.
A method for preparing a double density biopolymer foam, comprising:
- forming a biopolymer solution;
- crosslinking the biopolymer in the biopolymer solution without the use of crosslinking chemicals;
- freeze-drying the biopolymer solution to form a foam;
- washing the foam;
- shaping the foam to have a selected form;
- and
- drying the shaped foam, thereby forming a double density biopolymer foam.
Dependencies are inferred from the claim text.