Diagnostic for determining the time of a heart attack
AssigneeBiosite Diagnostics, Inc.
InventorsKenneth Francis Buechler, Paul H. McPherson
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Abstract
The present invention relates to methods for determining the time of a myocardial infarction in a patient by measuring the ratio of oxidized to reduced troponin I in a blood sample obtained from the patient. This ratio is measured through the use of two or more distinct components which specifically bind oxidized troponin I, reduced troponin I, and/or both forms of troponin I present in the blood sample. Each distinct component may be an antibody or an antibody fragment. The measured ratio reflects the time elapsed from the time of the myocardial infarction.
Claims19
A method for determining a time of a myocardial infarction in a patient, comprising a step of:
- determining a ratio of oxidized to reduced troponin I in a blood sample obtained from the patient within 24 hours of the myocardial infarction, where the ratio reflects an amount of time elapsed from the time of the myocardial infarction.
Dependencies are inferred from the claim text.