US 5,942,614 A · Process to produce midazolam

Abstract

The present invention discloses new processes in the preparation of midazolam (VII), ##STR1## a commercially important pharmaceutical, as well a new intermediates in those processes from a known benzophenone (I) starting material.

Claims1

Dependent claims

7-Chloro-5-(2-fl uorophenyl)-2,3-dihydro-1H-1,4-benzodiazepine-2-methanamine-4-oxide.

Dependencies are inferred from the claim text.

Facts

Application

09/063,110Filed 20 Jan 1998 · division

Priority

28 May 1997

Granted

24 Aug 1999

Term ends

Not estimatedThe source records don’t support an estimate.

Classification6 codes

C07D 487/04
In which the condensed system contains two hetero rings: ortho-condensed systems
C07C 257/06
Without replacement of the other oxygen atom of the carboxyl group, e.g. imino-ethers: having carbon atoms of imino-carboxyl groups bound to…
C07D 239/76
With only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to ring carbon atoms of the hetero ring: n-oxides
C07D 243/16
1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines: substituted in position 5 by aryl radicals

Process to produce midazolam

Life of this patent

Abstract

Claims1

Process to produce midazolam

Life of this patent

Abstract

Claims1