Cultivation of Paecilomyces sp. using silkworms

Abstract

Disclosed herein is a cultivation of Paecilomyces sp. which has various efficacies such as anti-tumor and reinforcement of immunity, but could not be used wide in human because of relatively limited supply. The artificial cultivation of Paecilomyces sp. comprises steps of (a) inoculating a dilution of spores of Paecilomyces sp. diluted with water to a concentration of 10.sup.7 .about.10.sup.8 spores/ml into a larva of 4th.about.5th instar of silkworm at a temperature of 26.about.30.degree. C. and a humidity of about 90% or more; and (b) inducing fruitbodies of Paecilomyces sp. by maintaining of the larvae at a temperature of 15.about.30.degree. C. and a humidity of about 90% or more. In particular, Paecilomyces japonica (KCCM-10117), Paecilomyces sp. J300 (KCCM-10116) and Paecilomyces farinosa (KCCM-10115).

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