Method of reversing immunosuppression in vaccines
AssigneeAmerican Cyanamid Company
InventorsMichael Joseph Daley, Phillip Wayne Hayes
Life of this patent
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Abstract
A method of reversing or preventing immunosuppression or antigenic interference associated with combination vaccines in mammals, is disclosed. Cytokines, or cytokine inducer, are administered in conjunction with the combination vaccine. The cytokine or cytokine inducer can be administered concurrently with or subsequently to the vaccine, and can be recombinantly produced or isolated from cell culture.
Claims20
A method of reducing or inhibiting antigenic interference associated with a vaccine comprising antigens from more than one pathogen in a mammal, said method comprising:
- administering in conjunction with the vaccine an IL-1 or an IL-1 inducer or a combination thereof in a pharmaceutically acceptable vehicle.
A method of reducing or inhibiting antigenic interference associated with a vaccine comprising antigens from more than onc pathogen in a mammal, comprising administering in conjunction with the vaccine an interleukin inducer, wherein the interleukin inducer is administered in a pharmaceutically acceptable vehicle.
A method of reversing or preventing antigenic interference in a mammal, wherein the antigenic interference is associated with a vaccine comprising antigens from more than one pathogen, said method comprising:
- administering in conjunction with the vaccine IL-1 or an IL-1 inducer or a combination thereof in a pharmaceutically acceptable vehicle.
Dependencies are inferred from the claim text.