Dietary composition for enhancing metabolism and alleviating oxidative stress
AssigneeThe Regents of the University of California
InventorsBruce N. Ames, Tory M. Hagen
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Abstract
The metabolic rate of aged cells of a mammalian host is enhanced without a concomitant increase in metabolic production of reactive oxygen species by orally administering to the host an effective dosage of a carnitine, such as acetyl-L-carnitine, and a mitochondrially active antioxidant, such as lipoic acid.
Claims10
A method for increasing the metabolic rate of aged cells without a concomitant increase in metabolic production of reactive oxygen species, comprising orally administering to a mammalian host an effective dosage of at least about 10 mg/kg host/day of a carnitine and at least about 10 mg/kg host/day of a mitochondrially active antioxidant which physiologically comprises a metabolically reactive thiol group.
An orally administratable dry unit dosage comprising at least about 250 mg of a carnitine and at least about 250 mg of a mitochondrially active antioxidant which physiologically comprises a metabolically reactive thiol group.
Dependencies are inferred from the claim text.