Controlled release container with core and outer shell
AssigneeDaratech Proprietary Limited
InventorsMichael F. O'Donoghue, James A. Morris
Life of this patent
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Abstract
A controlled release container includes an outer shell and a separately produced core that comprises at least one bioactive molecule. At least a portion of the outer shell comprises a biodegradable polymeric material that has a predetermined rate of degradation. The outer shell preferably is non-porous and provides a predetermined delay of at least two days from administration of the capsule before release of the active ingredient.
Claims26
A controlled release container comprising:
- an outer shell, at least a portion of which comprises a biodegradable polymeric material having a predetermined rate of degradation;
- and
- a core, enclosed by said outer shell, comprising at least one bioactive molecule as an active ingredient optionally admixed with at least one of a pharmaceutically acceptable carrier, a veterinarily acceptable carrier, and an excipient;
- said outer shell being produced separately from said core;
- said portion of said outer shell providing a predetermined delay of at least two days after administration of said controlled release container in the time period of release of said active ingredient.
An outer shell for a controlled release container, at least a portion of said outer shell comprising a biodegradable polymeric material having a predetermined rate of degradation, said portion of said outer shell providing a predetermined delay of at least two days after administration of said controlled release container in the time period of release of the contents of a core enclosed by said outer shell.
A method for producing a controlled release container, comprising the steps of:
- (i) producing a hollow outer shell by melt processing, at least a portion of said outer shell comprising a biodegradable polymeric material having a predetermined rate of degradation and providing a predetermined delay of at least two days after administration of said controlled release container in the time period of release of contents of a core enclosed by said outer shell;
- (ii) inserting a core into said outer shell, said core comprising at least one bioactive molecule as an active ingredient optionally admixed with at least one of a pharmaceutically acceptable carrier, a veterinarily acceptable carrier, and an excipient;
- and
- (iii) sealing said core within said hollow outer shell.
Dependencies are inferred from the claim text.