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US 5,914,387 AGranted
Polyesteramides with amino acid-derived groups alternating with alpha-hydroxyacid-derived groups and surgical articles made therefrom
AssigneeUnited States Surgical Corporation
InventorsMark S. Roby, Ying Jiang
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Abstract
Polyesteramides having amino acid-derived groups alternating with hydroxy acid-derived groups are useful in making shaped articles, particularly, shaped articles suitable for use as surgical devices.
Claims24
An esteramide compound having at least one unit of the general formula:
- ##STR6## wherein x is an integer from 1 to 6 and R is the same or different at each occurrence and is individually selected from the group consisting of hydrogen and C.sub.1 to C.sub.4 alkyl.
A method of making a polyesteramide comprising:
- a) blocking the amino group of an amino acid;
- b) halogenating the blocked amino acid to provide a chlorinated acid;
- c) reacting the halogenated acid with an alpha-hydroxy acid to provide a monomer;
- and
- d) de-blocking the product of step c);
- e) polymerizing the monomer to produce a polyesteramide.
3 more elements
A composition comprising:
- an esteramide compound having at least one unit of the general formula:
- ##STR11## wherein x is an integer from 1 to 6 and R is the same or different at each occurrence and is individually selected from the group consisting of hydrogen and C.sub.1 to C.sub.4 alkyl.
Dependencies are inferred from the claim text.