Temperature shock method and apparatus
OwnerJoel B. Graeinventor
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Abstract
A method for treating a biological organism in a medium, comprising heating the medium containing the organism by a temperature of at least about 2.degree. C. at a rate which exceeds a relaxation rate of a cellular membrane of that organism, under such time and temperature conditions which do not thermally denature a substantial portion of the biological proteins.
Claims23
A method for treating at least one cell of a biological organism in a medium with a thermal shock so as to alter processes within said cell, the cell having at least one membrane, and wherein the medium or the cell have biological proteins, comprising heating the medium containing the cell by a temperature of at least about 2.degree. C. at a rate which exceeds a relaxation rate of said at least one membrane of the at least one cell, under such time and temperature conditions which do not thermally denature a substantial portion of the biological proteins, and substantially without immediately killing the at least one cell.
A method for treating at least one cell of a biological organism in a medium with a thermal shock so as to alter processes within said cell and introducing said cell into an organism after the treatment, and wherein the medium or the cell have biological proteins, comprising heating the medium containing the cell by a temperature of at least about 2.degree. C. at a rate which exceeds a relaxation rate of said at least one membrane of the at least one cell, under such time and temperature conditions which do not thermally denature a substantial portion of the biological proteins, and substantially without immediately killing the at least one cell, and introducing the at least one treated cell into an organism after heating.
Dependencies are inferred from the claim text.