Alginate fibre, process for the preparation thereof and use
AssigneeBristol-Myers Squibb Company
InventorsPeter M. J. Mahoney, David Pritchard, Anne Elizabeth Howells, Bryan Griffiths
Life of this patent
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Abstract
Alginate fibres comprising at least one medicament incorporated into the structure thereof, the medicament being present at a level of at least 10% by weight, based on the weight of the alginate fibre with no incorporated medicament.
Claims19
Alginate fibres comprising at least one medicament incorporated into the structure thereof, the medicament being present at a level of at least 10% by weight, based on the weight of the alginate fibre with no incorporated medicament, and wherein the fibres are characterized by having two maxima in a plot of the first order derivative of percentage weight loss of the fibre with temperature against temperature in the range of 100 to 400.degree. C.
A method of treating a wound comprising the steps of applying a wound dressing comprising alginate fibre to a wound environment, the fibre comprising at least one medicament incorporated into the structure thereof, the medicament being present at a level of at least 10% by weight, based on the weight of the alginate fibre without incorporated medicament, and wherein the fibres are characterized by having two maxima in a plot of the first order derivative of percentage weight loss of the fibre with temperature against temperature in the range of 100 to 400.degree. C.
An alginate fabric formed in whole or in part from alginate fibres, said fibres comprising at least one medicament incorporated into the structure thereof, the medicament being present at a level of at least 10% by weight, based on the weight of the alginate fibre with no incorporated medicament, and wherein the fibres are characterized by having two maxima in a plot of the first order derivative of percentage weight loss of the fibre with temperature against temperature in the range of 100 to 400.degree. C.
A wound dressing formed in whole or in part from alginate fibre comprising at least one medicament incorporated into the structure thereof, the medicament being present at a level of at least 10% by weight, based on the weight of the alginate fibre with no incorporated medicament, and wherein the fibres are characterized by having two maxima in a plot of the first order derivative of percentage weight loss of the fibre with temperature against temperature in the range of 100 to 400.degree. C.
An implantation composition comprising an alginate fibre comprising at least one medicament incorporated into the structure thereof, the medicament being present at a level of at least 10% by weight, based on the weight of the alginate fibre with no incorporated medicament, and wherein the fibres are characterized by having two maxima in a plot of the first order derivative of percentage weight loss of the fibre with temperature against temperature in the range of 100 to 400.degree. C.
Dependencies are inferred from the claim text.