Method for development of transgenic dwarf goats
AssigneeNexia Biotechnologies, Inc.
InventorsCostas Karatzas, Carol Keefer, Jeffrey D. Turner
Life of this patent
Estimating the term…
Abstract
The invention features a method which includes the following steps: (a) introducing a transgene into a zygote of a dwarf goat, (b) transplanting the zygote into a pseudopregnant non-dwarf goat, and (c) allowing the zygote to develop to term. In another aspect the invention features a method which includes the following steps: (a) introducing a transgene into an embryo of a dwarf goat, (b) transplanting the embryo into a pseudopregnant non-dwarf goat, and (c) allowing the embryo to develop to term.
Claims6
A method for producing a transgenic dwarf goat whose somatic and germ cells comprise a transgene expressed in the mammary tissue of the transgenic dwarf goat, said method comprising:
- (a) introducing a transgene into a zygote or embryo of a dwarf goat, wherein said transgene comprises a DNA sequence encoding a protein in operable linkage with a promoter functional in mammary secretory cells,
- (b) transplanting said zygote or embryo into a pseudopregnant goat,
- (c) allowing said zygote or embryo to develop to term, and
- (d) identifying at least one dwarf goat, wherein expression of said transgene results in the production and secretion of a protein encoded by said DNA in the mammary tissue of said dwarf goat.
Dependencies are inferred from the claim text.