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US 5,907,039 AGranted
Amino alcohol derivative and method for preparing the same
AssigneeSeikagaku Kogyo Kabushiki Kaisha
InventorsMasayuki Jinbo, Hidekazu Oyamada, Jinichi Inokuchi
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Abstract
Amino alcohol derivatives with a primary amino group or a substituted amino group influence the synthesis of glycolipids and have antiviral, antitumor, metastasis inhibiting and neural cell growth enhancing functions. The amino alcohol derivatives are useful in preparing 2-acylamino alcohol derivatives.
Claims6
An amino alcohol derivative represented by the following formula (2):
- R.sup.2 --CH.sub.2 --(C*)H(HNP.sup.1)--(C*)H(OH)--R.sup.1 ( 2)
- wherein
- C* is an asymmetric carbon atom;
- P.sup.1 is an amino-protecting group selected from the group consisting of benzvloxycarbonyl groups which may have at least one substituent, alkoxycarbonyl groups which may have at least one substituent, and a benzenesulfonyl group;
- R.sup.1 is an alkyl group, a cycloalkyl group or an aryl group;
- and
- R.sup.2 is ##STR5## wherein R.sup.5 is a hydrogen atom or at least one substituent, and if two or more said substituents, said substituents are the same or different, wherein said substituent is a hydroxyl group, a lower alkyl group, a lower alkoxyl group, a hydroxyl-lower-alkyl group, a carboxyl group, a (lower alkoxyl) carbonyl group, an aralkyl group, a piperidino group, an acyloxy group, an amino group or an amino-lower-alkyl group;
- and
- m is an integer of 2 to 6.
6 more elements
Dependencies are inferred from the claim text.