Whole blood and platelet leukocyte filtration apparatus
AssigneeTeva Medical Ltd.
InventorsMenahem A. Kraus, Yephet Gamlieli, Jacob Yonath, Roni Hazan
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Abstract
A method for selectively removing leukocytes from a suspension which also contains platelets, such as a platelet concentrate or whole blood. The method includes passing the suspension through a filter which includes a polysaccharide-type coating. The coating may include one or more of hydroxypropylmethyl cellulose, hydroxybutylmethyl cellulose, dextran and hydroxyethyl starch. Also provided is a filter for selectively removing leukocytes from a suspension which also contains platelets. The filter includes a substrate which is coated with a polysaccharide-type composition.
Claims7
A filtering device with multiple layers for selectively removing leukocytes from a suspension which also contains platelets, wherein leukocytes are captured by the multiple layers, while the platelets pass through the device, the device comprising at least two layers of nitrocellulose membranes having a pore size of from about 5 to about 15 microns, and at least two layers of non-woven fibrous porous sheets, both said nitrocellulose membranes and said non-woven fibrous porous sheets being coated with at least one polysaccharide-type material.
A filtering device with multiple layers for selectively removing leukocytes from a suspension which also contains platelets, wherein leukocytes are captured by the multiple layers, while the platelets pass through the device, the device comprising at least three nitrocellulose membranes having a pore size of from about 5 to about 15 microns, and at least three layers of non-woven fibrous porous sheets, both said nitrocellulose membranes and said fibrous sheets being coated with at least one polysaccharide-type material.
Dependencies are inferred from the claim text.